Ganoderma lucidum can prevent tumor occurrence and inhibit tumor growth. It is reported that Ganoderma lucidum can inhibit the synthesis of DNA in cancer cells and has a direct inhibitory effect on the growth of cancer cells. Ganoderma lucidum can also promote blood fibrin to surround the tumor, blocking the supply of blood and nutrition to tumor cells, and thus inhibiting the growth of cancer cells. It was also found that the effects of Ganoderma lucidum on immunity and anti-cancer were also related to the dosage and concentration. Ganoderma lucidum can increase the secretion of tumor necrosis factor (TNF) by macrophages at a certain concentration. When the concentration is further increased, the secretion of TNF decreases.
Ganoderma lucidum has the effect of improving sleep, which may affect the secretion of melatonin in the pineal gland by regulating the nervous system through Ganoderma lucidum polysaccharides; Ganoderma lucidum polysaccharide also has significant SOD activity, promotes the removal of H2O2, has a scavenging effect on • OH -, can significantly remove the free radicals produced by the body, prevent the damage of free radicals to the body, and reduce the fatigue of the body. Therefore, the antioxidant effect may also be one of the mechanisms of Ganoderma lucidum to improve sleep; In addition, Ganoderma lucidum has an obvious sedative effect on the central nervous system, can reduce the spontaneous activity of animals, slightly relax muscles, and enhance the central inhibition of barbiturates, but it has no hypnotic or anesthetic effect, which may also be one of the reasons why Ganoderma lucidum can improve sleep.