Pharmacodynamic studies have proved that ligustrazine phthalide (50mg/kg, 25mg/gi. g.) can improve the behavior disorder of rats with cerebral ischemia caused by middle cerebral artery embolism in a dose-dependent manner, reduce the area of cerebral ischemia area, increase the cerebral blood flow of dogs, inhibit the formation of thrombus in rats and the aggregation of small blood plates in rats induced by ADP, and reduce the whole blood viscosity, plasma viscosity and hematocrit of rats; (100mg/kg, 50mg/gi. g μ G/ml) can effectively inhibit the proliferation of melanocytes, reduce the activity of tyrosinase, thereby reducing melanin synthesis, thus having a significant whitening effect.
Use of Chuanxiong oil
Light brown oily liquid [odor] has strong herb aroma [specific gravity] 0.9380-0.9682 [refraction] 1.459-1.470 [production process] supercritical carbon dioxide extraction [packaging specification] 25kg/plastic barrel [main ingredient] artemisinin 35% [efficacy] has the function of activating blood, promoting qi, removing wind and relieving pain. For irregular menstruation, amenorrhea, dysmenorrhea, abdominal pain, chest, and flank pain, tumbling pain, headache, rheumatic arthralgia, etc. [Features of this product] Natural, organic, and pollution-free.
Protective effect of ligusticum chuanxiong oil on cerebral ischemia-reperfusion injury in rats. The study showed that ligusticum chuanxiong oil could significantly reduce the energy score of nerve function and the volume of cerebral infarction in rats with ischemia-reperfusion injury; In addition, ligusticum chuanxiong oil can reduce the content of MDA and NO in the brain tissue of rats with cerebral ischemia-reperfusion injury, suggesting that ligusticum chuanxiong oil can reduce the free radical damage in the brain tissue after cerebral ischemia-reperfusion injury, to play its protective role on the brain tissue of rats with cerebral ischemia-reperfusion injury. In addition, ligusticum chuanxiong oil has the effect of reducing blood pressure, while water immersion of wattle has the effect of slightly reducing animal blood pressure, and intravenous or intramuscular injection after anesthesia can reduce blood pressure in dogs, cats, and rabbits.
