Changsha Staherb Magnolol Honokiol Magnolia Bark Extract R&D reference substance Study on the Pharmacological Activity of Reversarin from the Ethanol Extract of mangosteen — Changsha Staherb

Study on the Pharmacological Activity of Reversarin from the Ethanol Extract of mangosteen — Changsha Staherb

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Study on the Pharmacological Activity of Reversarin from the Ethanol Extract of mangosteen — Changsha Staherb

  1. Antioxidant effect

The mangosteen extract has good cosmetic and skincare effects, based on its ability to effectively remove excessive oxygen free radicals, enhance anti-wrinkle, and effectively delay skin aging. Among them, n-butanol solvent and ethyl acetate solvent have the best antioxidant activity.

  1. Antimicrobial effect

Mangosteen extract has a strong inhibitory effect on many pathogenic microorganisms in nature. It can inhibit the growth of Staphylococcus aureus, a common bacteria in dermatology, and some of its components also have an inhibitory effect on methicillin-resistant Staphylococcus aureus. The polysaccharide extract of Phyllostachys can stimulate phagocytes to kill the intracellular bacteria of Salmonella enteritidis, and stimulate white blood cells to play the role of phagocytosis and sterilization.

  1. Anti-inflammatory and anti-allergic effects

Two kinds of mangosteen flavonoids extracted from mangosteen, α、γ- Twistin has strong anti-inflammatory activity and can significantly inhibit the expression of nitric oxide products, dinoprostone products, and nitric oxide synthase in RAW264.7 cell line model stimulated by lipopolysaccharide. The study suggests that the two substances reduce the level of dinoprostone mainly by inhibiting the activity of cyclooxygenase-2 and nitric oxide products. For the rat paw edema model caused by carrageenin injection α- After 3 hours of treatment with twister, a significant inhibitory effect was found. γ- Twistin can inhibit the synthesis of prostaglandins in rat nerve cells. Therefore, these two substances have good anti-inflammatory effects and can be used as precursors for the development of new anti-inflammatory drugs. The study showed that 40% ethanol extract had a strong inhibitory effect on the release of histamine from RBL-2H3 cells mediated by immunoglobulin E. In addition, it also has an obvious inhibitory effect on the passive skin anaphylaxis of rats, indicating that the extract of bamboo has a good anti-histamine and anti-skin anaphylaxis effect. 4. Enhancement of immunity and anti-tumor effect The extract of bamboo also has the function of enhancing the immunity of the body and has a good inhibitory effect on the proliferation of various human tumors. Phyllostachys polysaccharide has phagocyte-like intracellular killing activity and participates in human immune function. Rattan flavone E has a strong cytotoxic effect on various hepatoma cell lines, as well as several gastric cancer and lung cancer cell lines.

author: staherb

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